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CASE REPORT
Year : 2016  |  Volume : 3  |  Issue : 3  |  Page : 124-127

Could zona-free blastocyst transfer be the next step in optimizing in vitro fertilization outcomes? A case report of successful outcome after zona-free fresh embryo transfer with preimplantation genetic screening


Lab.Director, Chief Embrylogist, Akanksha Hospital and Research Institute, Lambvel, Anand, Gujarat, India

Correspondence Address:
Harsha K Bhadarka
Akanksha Hospital and Research Institute, Lambvel, Anand, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2348-2907.204670

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The objective of this study was to study successful outcome after zona-free fresh embryo transfer with preimplantation genetic screening (PGS) in assisted reproductive technology. The study design was a case report. The study was conducted at in vitro fertilization (IVF) clinic. Patients with multiple IVF failure and miscarriage were included in the study. Zona-free fresh embryo transfer after PGS was intervened. The main outcome measure was live birth after IVF. In a PGS-indicated patient, zona-free chromosomally normal embryo was transferred and live healthy female baby weighing 2.7 kg was delivered.We report a case of natural complete hatching of an embryo after PGS, which was aided by mechanical breach of zona for trophectoderm biopsy. Carefully transferred zona-free embryo in a surrogate resulting in successful pregnancy and live birth which indicates that a good human blastocyst must have ability to expand in vitro and completely hatch out from zona after transfer for implantation.


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